Outcome following surgery for colorectal cancer: analysis by hospital after adjustment for case-mix and deprivation
2002

Colorectal Cancer Surgery Outcomes by Hospital

Sample size: 3200 publication Evidence: moderate

Author Information

Author(s): McArdle C S, Hole D J

Primary Institution: University Department of Surgery, Royal Infirmary, Glasgow

Hypothesis

Do significant differences in outcomes among hospitals persist after adjusting for case-mix and deprivation in colorectal cancer surgeries?

Conclusion

The study found significant differences in cancer-specific survival rates among hospitals even after adjusting for case-mix and deprivation.

Supporting Evidence

  • Significant differences in cancer-specific survival rates were found among hospitals.
  • Postoperative mortality rates did not significantly differ among hospitals.
  • Survival rates varied from 59% to 76% for curative resections across hospitals.

Takeaway

This study looked at how well patients do after colorectal cancer surgery in different hospitals and found that some hospitals have better outcomes than others, even when considering patient differences.

Methodology

The study analyzed data from 3200 patients who underwent colorectal cancer surgery in 11 hospitals, adjusting for various prognostic factors.

Potential Biases

Potential bias due to subjective interpretation of whether a resection was curative or palliative.

Limitations

The study's results may be influenced by subjective assessments of surgical outcomes and variations in pathological reporting.

Participant Demographics

35.1% of patients were aged 75 or over, and 19.2% were socio-economically deprived.

Statistical Information

Statistical Significance

p<0.001

Digital Object Identifier (DOI)

10.1038/sj.bjc.6600120

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