Evaluating the performance of the MSKCC gastric cancer survival calculator in the Turkish population
2024

Evaluating the MSKCC Gastric Cancer Survival Calculator in Turkey

Sample size: 489 publication Evidence: moderate

Author Information

Author(s): İlknur Deliktaş Onur, Tuğba Başoğlu, Nazım Can Demircan, Tuğba Akın Telli, Rukiye Arıkan, Özlem Ercelep, Mehmet Akif Öztürk, Perran Fulden Yumuk, Faysal Dane

Primary Institution: University of Health Sciences, Dr. Abdurrahman Yurtaslan Ankara Oncology Education and Research Hospital, Ankara, Turkiye

Hypothesis

This study aimed to evaluate the predictive power of the MSKCC nomogram in the Turkish patient population.

Conclusion

The MSKCC prognostic tool can be used to predict survival in clinical practice for gastric cancer patients who underwent surgery and R0 resection.

Supporting Evidence

  • The 5-year median observed OS rate was 51.7%, while the MSKCC tool estimated it at 48.5%.
  • The 9-year median observed OS rate was 41.4%, compared to 41% estimated by the MSKCC tool.
  • The study included gastric cancer patients aged 18 years or older who underwent primary curative surgery.
  • Statistically significant differences were found in survival rates based on age and tumor stage.

Takeaway

Doctors used a special calculator to predict how long patients with stomach cancer would live after surgery, and it worked pretty well for Turkish patients.

Methodology

The study analyzed the 5- and 9-year overall survival rates of gastric cancer patients who underwent primary curative surgery and R0 resection.

Potential Biases

The calculator does not include comorbidities, which may affect survival outcomes.

Limitations

The study was retrospective, and the adjuvant treatment protocols received by the patients were varied.

Participant Demographics

70.5% male and 29.5% female, mean age at diagnosis was 59.2 years.

Statistical Information

P-Value

0.0001

Confidence Interval

95% CI: 1.16–4.66

Statistical Significance

p = 0.31

Digital Object Identifier (DOI)

10.55730/1300-0144.5901

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