Fruit and Vegetable Consumption and Inflammatory Bowel Disease: A Case-Control Study
2024

Fruit and Vegetable Consumption and Inflammatory Bowel Disease

Sample size: 798 publication 10 minutes Evidence: moderate

Author Information

Author(s): Almofarreh Anas M., Sheerah Haytham A., Arafa Ahmed, Algori Fairuz A., Almutairi Ghonem R., Alenzi Kafi A., Al-Alsehemi Madiha M., Mekwar Banan H., Alzeer Osama, Molla Haneen N.

Primary Institution: Ministry of Health, Riyadh, Saudi Arabia

Hypothesis

This study investigates the association between fruit and vegetable consumption and the risk of ulcerative colitis and Crohn’s disease, focusing on gender-specific differences.

Conclusion

Daily vegetable consumption was significantly associated with decreased odds of Crohn’s disease among women, but not men.

Supporting Evidence

  • Daily vegetable consumption was associated with higher odds of UC in men but lost significance after adjustments.
  • Women who consumed vegetables daily had a significant inverse association with CD.
  • Fruit consumption was not associated with UC or CD in either sex.

Takeaway

Eating more vegetables might help women lower their chances of getting certain gut diseases, but it doesn't seem to help men in the same way.

Methodology

A hospital-based case-control study with 158 UC patients, 245 CD patients, and 395 controls, using logistic regression analysis.

Potential Biases

Potential bias due to the socioeconomic status of participants from a private institution.

Limitations

The study was conducted at a single polyclinic, which may limit generalizability, and dietary data were not validated.

Participant Demographics

The study included 516 men and 282 women, with varying ages and health conditions.

Statistical Information

P-Value

p<0.05

Confidence Interval

95% CI

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.3390/life14121524

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