Performing statistical analyses on quantitative data in Taverna workflows: An example using R and maxdBrowse to identify differentially-expressed genes from microarray data
2008

Using Taverna Workflows for Gene Analysis

publication Evidence: moderate

Author Information

Author(s): Li Peter, Castrillo Juan I, Velarde Giles, Wassink Ingo, Soiland-Reyes Stian, Owen Stuart, Withers David, Oinn Tom, Pocock Matthew R, Goble Carole A, Oliver Stephen G, Kell Douglas B

Primary Institution: University of Manchester

Hypothesis

Can Taverna workflows effectively analyze quantitative data from microarray experiments?

Conclusion

Taverna workflows allow data analysis experts to combine R scripts with other tools, enabling scientists to analyze their data without needing to learn programming.

Supporting Evidence

  • Taverna workflows can integrate various computational tools for data analysis.
  • The study demonstrated the use of R for statistical analysis within Taverna.
  • Workflows can be shared among scientists to facilitate data analysis without programming knowledge.

Takeaway

This study shows how scientists can use a tool called Taverna to analyze data from experiments without needing to know how to code. It helps them find important information in their data easily.

Methodology

The study used Taverna workflows to analyze microarray data by retrieving data from a database, performing statistical tests using R, and annotating results with Gene Ontology terms.

Limitations

The need for prior knowledge of R and Java programming may limit the ability of entry-level users to construct complex workflows.

Statistical Information

P-Value

<0.05

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1186/1471-2105-9-334

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