Horizontal Guided Bone Regeneration of the Posterior Mandible to Allow Implant Placement: 1‐Year Prospective Study Results
2024

Bone Regeneration for Dental Implants

Sample size: 45 publication 10 minutes Evidence: high

Author Information

Author(s): Lorenz Jonas, Ghanaati Shahram, Aleksic Zoran, Milinkovic Iva, Lazic Zoran, Magić Marko, Wessing Bastian, Grotenclos Ramona Schleich, Merli Mauro, Mariotti Giorgia, Bressan Eriberto, De Stavola Luca, Sader Robert

Primary Institution: Medical Center of the Goethe University Frankfurt

Hypothesis

Does horizontal ridge augmentation with guided bone regeneration using deproteinized bovine bone mineral support successful implant placement?

Conclusion

Guided bone regeneration using deproteinized bovine bone and a collagen membrane is a safe and effective method for augmenting bone in the mandible, allowing for successful implant placement.

Supporting Evidence

  • Of 45 patients evaluated 8 months post-GBR, 44 (97.8%) had sufficient bone for implant placement.
  • The mean bone width gain was 4.0 ± 1.5 mm at 1 mm from the crest.
  • The cumulative implant survival rate was 98.9% at 1 year.
  • Patients reported high satisfaction with implant function and esthetics.

Takeaway

Doctors can help people get dental implants by adding bone to their jaw using special materials, and this study shows it works really well.

Methodology

This was an open, prospective, single-cohort, multicenter clinical study assessing bone gain after guided bone regeneration in patients with ridge defects.

Potential Biases

Potential biases may arise from the multicenter design and the subjective nature of some outcome assessments.

Limitations

The study had a relatively short follow-up period and a small sample size for assessing the effects of wound dehiscence.

Participant Demographics

The majority of participants were females with a mean age of 50 years.

Statistical Information

P-Value

p<0.01

Statistical Significance

p<0.01

Digital Object Identifier (DOI)

10.1111/clr.14363

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