Isolated Foot Drop Due to a Cerebral Infarction Mimicking Lumbar Radiculopathy: A Case Report and Literature Review
2025

Isolated Foot Drop Due to a Cerebral Infarction

Sample size: 1 publication Evidence: low

Author Information

Author(s): Muacevic Alexander, Adler John R, Almutairi Abdulkarim A, Alqahtani Mishari S, Alsayari Mohammed A, Alamri Aser F

Primary Institution: Prince Sultan Military Medical City, Riyadh, SAU

Hypothesis

Can isolated foot drop be caused by central lesions like strokes instead of peripheral nerve damage?

Conclusion

Isolated foot drop can result from central causes such as cerebral infarction, highlighting the need for thorough diagnostic evaluations.

Supporting Evidence

  • Isolated foot drop is often linked to lower motor neuron lesions but can also be caused by upper motor neuron lesions.
  • Brain MRI revealed acute infarction in the right superior frontal gyrus.
  • The patient improved significantly after antiplatelet therapy and rehabilitation.

Takeaway

Sometimes, when someone can't lift their foot, it might not be because of a problem with their leg but because of an issue in their brain.

Methodology

The case involved clinical examination, MRI imaging of the brain and spine, and a review of literature on isolated foot drop.

Limitations

The study is based on a single case report, limiting generalizability.

Participant Demographics

An 83-year-old male with a history of diabetes and hypertension.

Digital Object Identifier (DOI)

10.7759/cureus.76894

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