ADAM: A Tool for Analyzing Biological Models
Author Information
Author(s): Hinkelmann Franziska, Brandon Madison, Guang Bonny, McNeill Rustin, Blekherman Grigoriy, Veliz-Cuba Alan, Laubenbacher Reinhard
Primary Institution: Virginia Bioinformatics Institute, Virginia Tech
Hypothesis
Can we create an efficient web-based tool to analyze complex biological models using discrete modeling techniques?
Conclusion
ADAM provides efficient analysis methods for complex biological models, making them accessible to a larger community.
Supporting Evidence
- ADAM identified attractors in complex discrete models in less than one second.
- The tool is platform independent and does not require installation.
- ADAM allows users to analyze models without needing to understand the underlying mathematics.
Takeaway
ADAM is a web tool that helps scientists understand complex biological systems by analyzing models quickly and easily, without needing to know complicated math.
Methodology
ADAM converts discrete models into polynomial dynamical systems and analyzes their dynamics using computer algebra techniques.
Limitations
The tool may not handle very large models efficiently and relies on the structure of biological systems being sparse.
Digital Object Identifier (DOI)
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