Dietary Cadmium Exposure and Ovarian Cancer Risk
Author Information
Author(s): B Julin, A Wolk, A Åkesson
Primary Institution: Karolinska Institutet
Hypothesis
Is there an association between dietary cadmium exposure and the risk of epithelial ovarian cancer?
Conclusion
The study suggests that dietary cadmium exposure is not likely to have a substantial role in ovarian cancer development.
Supporting Evidence
- 409 cases of epithelial ovarian cancer were identified during the study.
- The multivariable-adjusted rate ratio for the highest tertile of cadmium exposure was 0.90.
- No association was found for any subtype of ovarian cancer.
- The study had nearly complete follow-up through linkage to population-based registers.
Takeaway
Eating foods with cadmium doesn't seem to increase the chances of getting ovarian cancer.
Methodology
The study evaluated dietary cadmium exposure using food-frequency questionnaires and followed 60,889 women for 18.9 years to identify cases of ovarian cancer.
Potential Biases
Potential measurement error due to self-reported dietary intake.
Limitations
Self-reported dietary intake may introduce measurement error, and the study may not have captured the relevant exposure time for ovarian carcinogenesis.
Participant Demographics
Women born between 1914 and 1948 residing in Västmanland and Örebro counties of central Sweden.
Statistical Information
Confidence Interval
0.71–1.15
Digital Object Identifier (DOI)
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