Hookworm-Related Anaemia among Pregnant Women: A Systematic Review
2008

Hookworm-Related Anaemia among Pregnant Women: A Systematic Review

Sample size: 19 publication Evidence: moderate

Author Information

Author(s): Jennifer F. Friedman, Luz P. Acosta

Primary Institution: Center for International Health Research, Rhode Island Hospital and Department of Pediatrics, Brown University

Hypothesis

Hookworm treatment during pregnancy can improve maternal and infant health by addressing iron deficiency anaemia.

Conclusion

Hookworm infection during pregnancy is associated with lower hemoglobin levels, and treatment may help improve health outcomes for mothers and infants.

Supporting Evidence

  • Hookworm infection during pregnancy is linked to a significant decrease in hemoglobin levels.
  • Maternal iron deficiency can lead to increased risks of low birth weight and infant anaemia.
  • Treatment for hookworm may need to be combined with iron supplementation for better health outcomes.

Takeaway

Pregnant women with hookworm infections often have low iron levels, which can be harmful to both them and their babies, but treating the infection can help.

Methodology

The study included a meta-analysis of cross-sectional, observational, and randomized controlled trials to estimate the impact of hookworm on maternal anaemia.

Potential Biases

There is a risk of bias due to confounding factors such as diet and access to iron supplementation.

Limitations

The study's conclusions may be affected by the quality of the included studies and potential confounding factors related to poverty.

Participant Demographics

Pregnant women from lesser-developed countries.

Digital Object Identifier (DOI)

10.1371/journal.pntd.0000291

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