Study of a New Type I PRRSV in Pigs
Author Information
Author(s): Kim Hye Kwon, Lee Chul Seung, Kang Bo Kyu, Yeom Min Ju, Moon Hyoung Joon, Park Seong Jun, Nguyen Van Giap, Song Dae Sub, Park Bong Kyun
Primary Institution: Seoul National University
Hypothesis
What is the virulence of a newly emerging type I PRRSV isolate in colostrum-deprived pigs?
Conclusion
The study found that the Korean type I PRRSV strain caused classical PRRSV-specific lesions in pigs.
Supporting Evidence
- The pneumonia was more severe in type I PRRSV-infected pigs than in type II PRRSV-infected pigs.
- PRRS-specific antibodies were detected within the first week after challenge.
- Viremia continued at least until 21 days post challenge in both groups.
Takeaway
Researchers gave a new virus to baby pigs to see how sick it would make them, and they found it made them very sick.
Methodology
Colostrum-deprived pigs were infected with a type I PRRSV isolate and evaluated for gross and histopathological lesions over 21 days.
Limitations
Only one strain of type I PRRSV was evaluated, limiting the generalizability of the findings.
Participant Demographics
Colostrum-deprived pigs, 3 weeks old.
Digital Object Identifier (DOI)
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