Incidence and survival for cancer in children and young adults in the North of England, 1968–1995: a report from the Northern Region Young Persons’ Malignant Disease Registry
2000

Cancer Incidence and Survival in Children and Young Adults in Northern England

Sample size: 4316 publication Evidence: moderate

Author Information

Author(s): Cotterill S J, Parker L, Malcolm A J, Reid M, More L, Craft A W

Primary Institution: Department of Child Health, University of Newcastle upon Tyne

Hypothesis

How have cancer incidence and survival rates changed for children and young adults in Northern England from 1968 to 1995?

Conclusion

There were significant improvements in survival rates and modest increases in cancer incidence for both children and young adults over the studied period.

Supporting Evidence

  • 2099 children and 2217 young adults were diagnosed with cancer between 1968 and 1995.
  • The age-standardized rate for childhood cancer was 121 per million per year.
  • The age-standardized rate for young adults was 175 per million per year.
  • 5-year survival rates for childhood cancer improved from 42% to 71% over the study period.
  • 5-year survival rates for young adults improved from 45% to 73% over the study period.
  • The cumulative risk of developing cancer before age 25 is 1 in 285.

Takeaway

This study looked at how many kids and young adults got cancer and how many survived it in Northern England over a long time. It found that more people are getting cancer, but more are also surviving it.

Methodology

The study analyzed data from the Northern Region Young Persons’ Malignant Disease Registry for cancer cases diagnosed between 1968 and 1995.

Participant Demographics

Children aged 0-14 years and young adults aged 15-24 years diagnosed with cancer.

Statistical Information

P-Value

p<0.001

Confidence Interval

95% CI 67–75 for childhood cancer; 95% CI 70–78 for young adults

Statistical Significance

p<0.001

Digital Object Identifier (DOI)

10.1054/bjoc.2000.1313

Want to read the original?

Access the complete publication on the publisher's website

View Original Publication