Plasma 25-Hydroxyvitamin D Is Independently Associated with Hemoglobin Concentration in Male Subjects with Type 2 Diabetes Mellitus
2011

Vitamin D and Hemoglobin Levels in Men with Type 2 Diabetes

Sample size: 106 publication Evidence: moderate

Author Information

Author(s): Meguro Shu, Tomita Masuomi, Katsuki Takeshi, Kato Kiyoe, Oh Henpiru, Ainai Akira, Ito Ryo, Takeda Shu, Kawai Toshihide, Atsumi Yoshihito, Itoh Hiroshi, Hasegawa Hideki

Primary Institution: Keio University

Hypothesis

There is a relationship between anemia of diabetes mellitus and vitamin D status.

Conclusion

Vitamin D levels are significantly associated with hemoglobin concentration in men with type 2 diabetes, independent of kidney function and nutrition markers.

Supporting Evidence

  • Hemoglobin concentration was positively correlated with vitamin D levels.
  • Multiple regression analysis showed vitamin D's independent relation to hemoglobin concentration.
  • Vitamin D deficiency may directly relate to anemia in diabetes.

Takeaway

This study found that having enough vitamin D is important for men with diabetes because it helps keep their blood healthy.

Methodology

A cross-sectional study analyzing the correlation between plasma 25-hydroxyvitamin D levels and hemoglobin concentration in male patients with type 2 diabetes.

Potential Biases

Selection bias may be present due to non-random sampling of participants.

Limitations

The study's cross-sectional design limits causal inference, and the sample size was small and not randomly selected.

Participant Demographics

All participants were Japanese males with type 2 diabetes, average age 64.5 years.

Statistical Information

P-Value

<0.01

Statistical Significance

p<0.01

Digital Object Identifier (DOI)

10.1155/2011/362981

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