Disparities in time to treatment initiation of invasive lung cancer among Black and White patients in Tennessee
2023

Disparities in Lung Cancer Treatment Timing in Tennessee

Sample size: 42970 publication 10 minutes Evidence: moderate

Author Information

Author(s): Mamudu Lohuwa, Sulley Saanie, Atandoh Paul H., Reyes Joanne L., Bashar Raquibul A. K. M., Whiteside Martin, McEligot Archana J., Mamudu Hadii M., Williams Faustine

Primary Institution: Division of Intramural Research, National Institute on Minority Health and Health Disparities, National Institutes of Health

Hypothesis

Black patients with invasive lung cancer would experience longer times to treatment initiation than their White counterparts.

Conclusion

Black patients were often at greater risk of late initiation of treatment for invasive lung cancer in Tennessee.

Supporting Evidence

  • Black patients aged <45 years had a 40% increased risk of delayed treatment initiation compared to those aged ≥75 years.
  • Patients with private insurance were 8% more likely to delay treatment compared to self-pay/uninsured patients.
  • Individuals diagnosed with localized lung cancer had a decreased risk of delayed treatment compared to those diagnosed at the distant stage.

Takeaway

This study found that Black patients in Tennessee often wait longer to start treatment for lung cancer compared to White patients, which can affect their chances of survival.

Methodology

The study analyzed population-based registry data of 42,970 individuals diagnosed with invasive lung cancer from the Tennessee Cancer Registry, using bivariate ANOVA tests and multivariable Cox proportional hazard models.

Potential Biases

Potential biases may arise from the administrative data used, which did not capture all relevant variables affecting treatment timing.

Limitations

The study is limited by its cross-sectional design and lack of specific data on types of treatment delays and individual-level socioeconomic status.

Participant Demographics

The sample included 4,480 Black and 38,490 White patients diagnosed with invasive lung cancer in Tennessee.

Statistical Information

Confidence Interval

95% CI

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1371/journal.pone.0311186

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