HPV-66 and Vulvar Cancer: A Case Report
Author Information
Author(s): Kotsopoulos Ioannis C, Tampakoudis Georgios P, Evaggelinos Dimitrios G, Nikolaidou Anastasia I, Fytili Panagiota A, Kartsiounis Vasilios C, Gerasimidou Domniki K
Primary Institution: Theagenio Cancer Hospital
Hypothesis
Can HPV-66 be a causative factor in vulvar carcinoma?
Conclusion
HPV-66 can be regarded as a causative factor in vulvar carcinoma, despite HPV-16 and HPV-18 being more commonly implicated.
Supporting Evidence
- HPV-66 is a rare type of α-papillomavirus.
- The patient underwent radical vulvectomy and bilateral inguinal lymphadenectomy.
- Histopathological examination confirmed squamous cell carcinoma grade II/III.
Takeaway
This study talks about an 80-year-old woman who had vulvar cancer caused by a rare virus called HPV-66, which is not usually linked to this type of cancer.
Methodology
The case involved histological and cytological examinations, HPV DNA typing, and PCR assays.
Limitations
The study is based on a single case report, limiting generalizability.
Participant Demographics
An 80-year-old Greek Caucasian woman.
Digital Object Identifier (DOI)
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