Using Blood Ratios to Differentiate Appendicitis Types in Kids
Author Information
Author(s): Anastasakis Michail, Trevlias Ioannis, Farmakis Konstantinos, Valioulis Ioannis, Kambouri Katerina
Primary Institution: 1st Department of Pediatric Surgery, Aristotle University of Thessaloniki, Greece
Hypothesis
Can the Neutrophil-to-Lymphocyte Ratio (NLR) and Platelet-to-Lymphocyte Ratio (PLR) effectively differentiate between complicated and uncomplicated appendicitis in children?
Conclusion
The study found that NLR and PLR are significantly associated with acute perforated appendicitis, suggesting their potential as diagnostic tools.
Supporting Evidence
- 27.5% of patients had complicated appendicitis.
- NLR values > 7.92 had a sensitivity of 62.5% and specificity of 74.2%.
- PLR values > 180.57 had a sensitivity of 61.1% and specificity of 68.9%.
- The area under the curve for NLR was 0.736, indicating good diagnostic performance.
- The study included children up to 16 years old who underwent appendectomy.
Takeaway
Doctors can use two blood tests to help tell if kids have a serious type of appendicitis or a milder one, which can help them decide on treatment.
Methodology
A retrospective review of medical records of 341 children with suspected acute appendicitis was conducted, analyzing NLR and PLR values.
Potential Biases
Potential biases may arise from the retrospective nature of the study and reliance on medical records.
Limitations
The study is retrospective and single-center, which may limit the generalizability of the findings.
Participant Demographics
The study included 282 pediatric patients, with a mean age of 10 years and 9 months, consisting of 62.2% males and 37.8% females.
Statistical Information
P-Value
0.000
Confidence Interval
0.666 to 0.805
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
Want to read the original?
Access the complete publication on the publisher's website