Molecular Basis of Obesity: Current Status and Future Prospects
Author Information
Author(s): Choquet Hélène, Meyre David
Primary Institution: Ernest Gallo Clinic and Research Center, University of California, San Francisco; McMaster University, Canada
Hypothesis
Obesity is a heritable disorder influenced by both genetic and environmental factors.
Conclusion
The study highlights the complex genetic architecture of obesity and the need for further research to identify additional genetic factors.
Supporting Evidence
- Obesity prevalence has increased significantly worldwide over the past few decades.
- Genetic factors play a substantial role in determining individual susceptibility to obesity.
- Nine loci have been identified in Mendelian forms of obesity, and 58 loci are associated with polygenic obesity.
Takeaway
Obesity can run in families because of genes, and scientists are trying to find out more about the genes that make people gain weight.
Methodology
The review summarizes findings from various studies on the genetic and environmental factors contributing to obesity.
Limitations
The review does not provide new experimental data but synthesizes existing literature.
Digital Object Identifier (DOI)
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