Expression of interleukin-17RC protein in normal human tissues
2008
Study of IL-17RC Protein in Human Tissues
Sample size: 53
publication
Evidence: moderate
Author Information
Author(s): Ge Dongxia, You Zongbing
Primary Institution: Tulane University
Hypothesis
The study aims to systematically examine IL-17RC protein expression in human tissues.
Conclusion
IL-17RC protein is expressed in most human tissues, indicating its potential role in various biological processes.
Supporting Evidence
- IL-17RC protein was expressed in many cell types including myocardial cells and various glandular and epithelial cells.
- High levels of IL-17RC expression were observed in vascular and lymphatic endothelium.
- IL-17RC was not detectable in certain cell types such as smooth muscle cells and neurons.
Takeaway
The study looked at a protein called IL-17RC in many human tissues and found it is present in most of them, which might mean it has important jobs in the body.
Methodology
The expression of IL-17RC was determined using immunohistochemical staining on tissue microarrays.
Limitations
The study did not explore the functional role of IL-17RC in the tissues where it was expressed.
Digital Object Identifier (DOI)
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