Safety of Adenosine Stress Perfusion Cardiac MRI in Aortic Stenosis Patients
Author Information
Author(s): Darty Stephen
Primary Institution: Duke Cardiovascular Magnetic Resonance Center
Hypothesis
The study aims to determine the safety of adenosine perfusion cardiac magnetic resonance imaging in patients with aortic stenosis.
Conclusion
Adenosine perfusion CMR is a safe alternative for non-invasive stress testing in patients with mild to severe aortic stenosis.
Supporting Evidence
- 16% of patients had severe aortic stenosis.
- Only 2 transient adverse events occurred during the study.
- 51% of patients had stress CMR studies indicative of significant coronary artery disease.
Takeaway
Doctors wanted to see if a special heart test using adenosine is safe for patients with a heart valve problem. They found it is safe to use.
Methodology
Consecutive patients with known or suspected coronary artery disease and native aortic valve stenosis underwent adenosine perfusion CMR.
Limitations
The study only included patients with known or suspected coronary artery disease and may not be generalizable to all patients with aortic stenosis.
Participant Demographics
Mean age 76 years, 52% female.
Statistical Information
Confidence Interval
0-2.6% for severe adverse events; 0.3-5.5% for transient events.
Digital Object Identifier (DOI)
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