Mitochondrial Genomics of Killifish
Author Information
Author(s): Andrew Whitehead
Primary Institution: Louisiana State University
Hypothesis
Different mitochondrial genotypes are favored by natural selection in different osmotic environments.
Conclusion
Mitochondrial genome evolution in killifish is mainly influenced by strong purifying selection and demographic factors.
Supporting Evidence
- Mitochondrial genes evolve at variable rates, but all genes exhibit very low dN/dS ratios across all lineages.
- No signals of directional selection or hybridization were detected.
- The southern population harbors more synonymous polymorphism than other populations.
Takeaway
This study looks at how the DNA in the mitochondria of killifish changes based on where they live and how they handle salt in the water.
Methodology
Complete mitochondrial genomes were sequenced from various populations of Fundulus heteroclitus and related species, and comparative genomics approaches were used to analyze the data.
Limitations
Limited phylogenetic sampling with only five taxa may affect the power to detect positive selection.
Participant Demographics
Populations sampled included northern, southern, and fresh water populations of Fundulus heteroclitus.
Statistical Information
P-Value
p<0.001
Statistical Significance
p<0.001
Digital Object Identifier (DOI)
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