Antioxidant and Anti-Inflammatory Activities of Eriosema montanum Extract
Author Information
Author(s): Tabakam Gaétan Tchangou, Njoya Emmanuel Mfotie, Chukwuma Chika Ifeanyi, Mashele Samson Sitheni, Nguekeu Yves Martial Mba, Tene Mathieu, Awouafack Maurice Ducret, Makhafola Tshepiso Jan
Primary Institution: Central University of Technology, Bloemfontein, South Africa
Hypothesis
The study investigates the antioxidant and anti-inflammatory potentials of the Eriosema montanum methanolic extract and its isolated compounds.
Conclusion
The study found that the methanolic extract of Eriosema montanum exhibits moderate antioxidant and anti-inflammatory activities, with specific fractions showing higher efficacy.
Supporting Evidence
- EMME had moderate antioxidant and anti-inflammatory activities.
- Fraction FF showed much higher efficacy with specific IC50 values against various radicals.
- Genistin was identified as the most concentrated compound in the extract.
Takeaway
This study shows that a plant called Eriosema montanum can help fight inflammation and protect against damage from harmful substances in the body.
Methodology
The study used in vitro and cellular models to evaluate antioxidant and anti-inflammatory activities, including various assays to measure phenolic and flavonoid contents.
Limitations
The study did not explore the long-term effects or the clinical implications of the findings.
Statistical Information
P-Value
p<0.05
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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