Trans-arterial hepatic radioembolisation of yttrium-90 microspheres
2006

Yttrium-90 Microspheres for Liver Cancer Treatment

publication 10 minutes Evidence: moderate

Author Information

Author(s): Murthy R MD, FACP, Habbu A MD, Salem R MD, MBA, FSIR

Primary Institution: Department of Biomedical Imaging, Faculty of Medicine, University of Malaya, Malaysia

Hypothesis

Can yttrium-90 microspheres improve treatment outcomes for patients with liver cancer?

Conclusion

Yttrium-90 microspheres are an effective therapy for liver cancer, showing positive responses in tumor reduction and survival.

Supporting Evidence

  • Yttrium-90 microspheres can deliver high doses of radiation directly to liver tumors.
  • Patients treated with Y90 microspheres showed improved survival rates compared to those receiving standard treatments.
  • Clinical trials demonstrated significant tumor response rates with the use of Y90 microspheres.

Takeaway

Doctors use tiny beads filled with radiation to treat liver cancer, helping to shrink tumors and improve patient health.

Methodology

The review discusses the therapeutic principles, patient exclusion criteria, and clinical results of yttrium-90 microsphere therapy for liver cancer.

Potential Biases

Potential bias in patient selection and treatment response reporting.

Limitations

The study does not address the optimal patient selection or the ideal radiation dose and frequency.

Participant Demographics

Patients with unresectable metastatic colorectal cancer and hepatocellular carcinoma.

Statistical Information

P-Value

p<0.01

Statistical Significance

p<0.01

Digital Object Identifier (DOI)

10.2349/biij.2.3.e43

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