Matrix Metalloproteinase-2 and -9 Secreted by Leukemic Cells Increase the Permeability of Blood-Brain Barrier by Disrupting Tight Junction Proteins
2011

Leukemic Cells and Blood-Brain Barrier Permeability

publication

Author Information

Author(s): Feng Saran, Cen Jiannong, Huang Yihong, Shen Hongjie, Yao Li, Wang Yuanyuan, Chen Zixing

Supporting Evidence

  • This study is supported by the National Key Scientific Project of China (973 Program #2011CB933500).
  • The study is also supported by the Priority Academic Program Development of Jiangsu Higher Education Institutions, PAPD.

Takeaway

Leukemic cells can make the blood-brain barrier more leaky, which might cause problems in the brain.

Want to read the original?

Access the complete publication on the publisher's website

View Original Publication