4-[2-(Benzyl­ sulfan­yl)acet­yl]-3,4-dihydro­quinoxalin-2(1H)-one
2011

Study of a New Quinoxalinone Compound

publication

Author Information

Author(s): Nasir Waqar, Munawar Munawar Ali, Nadeem Sohail, Amjad Rana, Adnan Ahmad

Primary Institution: Institute of Chemistry, University of the Punjab, Lahore, Pakistan

Hypothesis

The study aimed to synthesize novel quinoxalinone derivatives with enhanced biological and pharmaceutical applications.

Conclusion

The synthesized compound exhibits specific structural characteristics and intermolecular interactions that may contribute to its biological activity.

Supporting Evidence

  • The compound's structure includes a non-planar pyrazinone ring.
  • Intermolecular hydrogen bonding forms inversion dimers.
  • The dihedral angles between the rings indicate specific orientations.

Takeaway

The researchers made a new chemical compound that might be useful in medicine, and they studied its structure to understand how it works.

Methodology

The compound was synthesized using a reaction of 4-(chloroacetyl)-3,4-dihydroquinoxalin-2(1H)-2-one with sodium bicarbonate and phenylmethanethiol in ethanol, followed by crystallization.

Digital Object Identifier (DOI)

10.1107/S1600536811008178

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