Biological Sex Moderates the Effect of Exercise on Cognitive Function in Adults with Chronic Stroke
2024

Exercise Helps Cognitive Function in Women After Stroke

Sample size: 120 publication Evidence: moderate

Author Information

Author(s): Gamboa Rebeca Hernández, Falck Ryan, Dao Elizabeth, Liu-Ambrose Teresa

Primary Institution: University of British Columbia

Hypothesis

Does biological sex moderate the effects of exercise and cognitive/social enrichment on cognitive function in adults with chronic stroke?

Conclusion

Exercise may be a key strategy to promote cognitive function among older females living with stroke.

Supporting Evidence

  • Biological sex moderated the effect of exercise on cognitive function.
  • The effects of exercise compared to balance and tone control were significantly larger for females than males.
  • Exercise females had better cognitive performance at the end of the intervention compared to females in the control group.

Takeaway

Doing exercise can help older women who have had a stroke think better, more than it helps men.

Methodology

A secondary analysis of a three-arm, six-month, assessor-blinded, randomized clinical trial.

Participant Demographics

Community-dwelling adults aged 55+ years with chronic stroke.

Statistical Information

P-Value

p<0.005

Confidence Interval

95% CI: -0.778, -0.011

Statistical Significance

p<0.01

Digital Object Identifier (DOI)

10.1093/geroni/igae098.0519

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