A Cohort Study of Traffic-Related Air Pollution Impacts on Birth Outcomes
2008

Traffic-Related Air Pollution and Birth Outcomes

Sample size: 70249 publication 10 minutes Evidence: moderate

Author Information

Author(s): Michael Brauer, Cornel Lencar, Lillian Tamburic, Mieke Koehoorn, Paul Demers, Catherine Karr

Primary Institution: The University of British Columbia

Hypothesis

Does air pollution exposure adversely affect pregnancy outcomes such as small for gestational age (SGA) birth weight, low full-term birth weight (LBW), and preterm birth?

Conclusion

Traffic-related air pollution is associated with increased risks of small for gestational age and low birth weight in a population-based cohort.

Supporting Evidence

  • Residence within 50 m of highways was associated with a 26% increase in SGA.
  • An 11% increase in LBW was observed for those living close to highways.
  • Exposure to air pollutants except ozone was linked to SGA.
  • Associations were consistent across different exposure estimation methods.

Takeaway

Living close to busy roads can make babies smaller and lighter when they are born.

Methodology

The study used linked administrative data to analyze 70,249 singleton births and estimated air pollution exposure using various models.

Potential Biases

Potential misclassification of exposure due to residential mobility and reliance on neighborhood-level socioeconomic data.

Limitations

The study relied on administrative data, which may not capture all relevant individual-level factors, and exposure was based only on residential address.

Participant Demographics

The cohort included 51.4% male births, with a mean maternal age of 31.1 years and 7.4% reporting maternal smoking during pregnancy.

Statistical Information

P-Value

p<0.05

Confidence Interval

95% CI, 1.07–1.49 for SGA; 95% CI, 1.01–1.23 for LBW

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1289/ehp.10952

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