Outcomes of Surgery for Pancreatic Adenosquamous Carcinoma
Author Information
Author(s): Hsu Jun-Te, Chen Han-Ming, Wu Ren-Chin, Yeh Chun-Nan, Yeh Ta-Sen, Hwang Tsann-Long, Jan Yi-Yin, Chen Miin-Fu
Primary Institution: Chang Gung Memorial Hospital, Chang Gung University College of Medicine
Hypothesis
What are the clinicopathological features and outcomes of pancreatic adenosquamous carcinoma patients after surgery?
Conclusion
Aggressive surgical management does not appear effective in treating pancreatic ASC patients.
Supporting Evidence
- Symptoms included abdominal pain (91.7%) and body weight loss (83.3%).
- Median survival of 12 patients was 4.41 months.
- Seven patients receiving surgical resection had median survival of 6.51 months.
- Patients with stage IIB pancreatic ASC had shorter median survival compared to those with adenocarcinoma.
Takeaway
Pancreatic adenosquamous carcinoma is a rare type of cancer that doesn't respond well to surgery, and most patients don't live long after treatment.
Methodology
The medical records of 12 patients with pancreatic ASC undergoing surgical treatment were retrospectively reviewed.
Limitations
The study is based on a retrospective review and does not include patients treated non-surgically.
Participant Demographics
5 men and 7 women, age range 32 to 79 years, median age 71 years.
Statistical Information
P-Value
0.018
Confidence Interval
0.0–24
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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