Nonbacterial thrombotic endocarditis associated with cancer: a case report
Author Information
Author(s): Norisada Kazuko, Tanaka Hidekazu, Onishi Tetsuari, Kaneko Akihiro, Tsuji Takayuki, Yamawaki Kohei, Ryo Keiko, Tatsumi Kazuhiro, Matsumoto Kensuke, Miura Natsuko, Saegusa Jun, Morinaga Yukiko, Hara Shigeo, Kawai Hiroya, Hirata Ken-ichi
Primary Institution: Kobe University Graduate School of Medicine
Conclusion
The patient was diagnosed with nonbacterial thrombotic endocarditis associated with cancer of unknown origin, complicated by a thrombus in the left auricular appendage.
Supporting Evidence
- Nonbacterial thrombotic endocarditis is a rare condition associated with cancer.
- The patient developed multiple brain embolic infarctions after being diagnosed with metastatic colon cancer.
- Transesophageal echocardiography revealed mobile masses on the mitral valve and a thrombus in the left auricular appendage.
- Histological analysis showed that the masses were mainly composed of fibrin without bacteria.
- The diagnosis of nonbacterial thrombotic endocarditis is often made at autopsy.
Takeaway
This study talks about a man who had a rare heart condition linked to cancer, which caused blood clots in his heart and brain.
Methodology
The case was evaluated through physical examination, imaging studies, and autopsy.
Limitations
The diagnosis of nonbacterial thrombotic endocarditis is often made post-mortem, making it difficult to diagnose during life.
Participant Demographics
A 63-year-old man with a history of hypertension, hyperlipidemia, and chronic rheumatoid arthritis.
Digital Object Identifier (DOI)
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