Comparison of Treatment Plans for Palliative Spinal Bone Irradiation
Author Information
Author(s): Andic Fundagul, Baz Cifci Sule, Ors Yasemin, Niang Umar, Dirier Ahmet, Adli Mustafa
Primary Institution: Department of Radiation Oncology, Faculty of Medicine, Gaziantep University, Gaziantep, Turkey
Hypothesis
This study aimed to analyze three-dimensional dosimetric data of palliative spinal bone irradiation using different reference points and treatment plans.
Conclusion
In palliative spinal bone irradiation, 2D conventional single posterior field radiotherapy did not accomplish the ICRU Report 50 recommendations for PTV dose distribution, while the AP-PA field plans did achieve the intended dose ranges with a homogenous distribution.
Supporting Evidence
- AP-PA field plans achieved the intended dose ranges and homogeneity for PTVs.
- Minimum doses of both single field plans were significantly lower than AP-PA field plans.
- Maximum doses for medulla spinalis were higher than 120% of the prescribed dose in 49% of IBMCrp single field plans.
Takeaway
Doctors compared different ways to give radiation to the spine to help with pain from cancer. They found that one method worked better than the others.
Methodology
Forty-five simulation CT scans of 39 patients were analyzed using three different treatment plans for palliative spinal bone irradiation.
Limitations
The study may not generalize to all patients with spinal bone metastases due to the specific treatment plans and dosimetric assessments used.
Participant Demographics
Patients previously treated for thoraco-lumbar spinal bone metastases.
Statistical Information
P-Value
p<0.001
Statistical Significance
p<0.001
Digital Object Identifier (DOI)
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