Coccidioidal Placentitis and Normal Umbilical Artery Velocimetry
Author Information
Author(s): Stephen A. Nickisch, Luis Izquierdo, Maggie A. Viii, Luis Curet, Gordon C. Wolf
Primary Institution: University of New Mexico School of Medicine
Hypothesis
Coccidioidal placentitis might lead to measurable placental resistance values due to characteristic changes like infarction and necrosis.
Conclusion
Coccidioidal placentitis was successfully treated with amphotericin B, and monitoring showed no abnormalities, allowing the pregnancy to continue to term.
Supporting Evidence
- Serial umbilical artery velocimetry revealed normal systolic/diastolic ratios.
- The infant was delivered at term and weighed 3,130 g with high APGAR scores.
- Histological confirmation of coccidioidal placentitis was obtained.
Takeaway
A pregnant woman with a rare infection had a healthy baby after treatment, and tests showed her placenta was working fine.
Methodology
The case involved treatment with systemic and intrathecal amphotericin B and serial umbilical artery velocimetry monitoring.
Limitations
The study is based on a single case, limiting generalizability.
Participant Demographics
27-year-old Hispanic female, G2PoAb.
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