Episcleritis from Drug-Induced Lupus after Infliximab Treatment
Author Information
Author(s): Irini P. Chatziralli, Evgenia Kanonidou, Alexandros Chatzirallis, Prodromos Dimitriadis, Petros Keryttopoulos
Primary Institution: General Hospital of Veroia, Greece
Hypothesis
Can infliximab therapy lead to drug-induced lupus erythematosus with ocular manifestations?
Conclusion
The case highlights that symptoms of drug-induced lupus erythematosus should not be overlooked, especially when associated with infliximab therapy.
Supporting Evidence
- The patient had a history of Crohn's disease and was treated with infliximab.
- Symptoms of drug-induced lupus erythematosus developed after one year of infliximab therapy.
- Laboratory tests showed positive antinuclear antibodies and anti-dsDNA antibodies.
- Symptoms improved after discontinuation of infliximab and treatment with prednisone.
Takeaway
A woman developed eye problems and other symptoms after taking a medicine called infliximab, but her issues got better when she stopped the medicine.
Methodology
Case report detailing the clinical presentation, laboratory findings, and treatment outcomes of a patient.
Limitations
Only one case is reported, limiting generalizability.
Participant Demographics
A 42-year-old woman with Crohn's disease.
Digital Object Identifier (DOI)
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