Clinical Evidence of the Efficacy of a Mouthwash Containing Propolis for the Control of Plaque and Gingivitis: A Phase II Study
2011

Efficacy of Propolis Mouthwash for Plaque and Gingivitis Control

Sample size: 25 publication 10 minutes Evidence: moderate

Author Information

Author(s): Elizete Maria Rita Pereira, João Luís Duval Cândido, Fernando Freitas Silva, Mariana Passos De Luca, Efigênia Ferreira Ferreira, Telma Campos Medeiros Lorentz, Vagner Rodrigues Santos

Primary Institution: Federal University of Minas Gerais

Hypothesis

Does an alcohol-free mouthwash containing 5% Brazilian green propolis effectively control plaque and gingivitis?

Conclusion

The study found that the mouthwash significantly reduced plaque and gingivitis over 90 days.

Supporting Evidence

  • The mouthwash showed a 40% reduction in gingivitis after 90 days.
  • Plaque levels decreased by over 70% compared to baseline scores.
  • Participants reported no significant side effects from using the mouthwash.

Takeaway

This study tested a mouthwash made with propolis, which is a natural substance from bees, and found it helps keep your teeth and gums healthy.

Methodology

A phase II interventional study with 25 participants using a mouthwash containing 5% Brazilian green propolis for three months.

Potential Biases

Potential bias due to the convenience sampling method and self-reported compliance.

Limitations

The study faced limitations such as unexpected reactions to the product and difficulties in monitoring participant compliance.

Participant Demographics

Participants were men and women aged 18 to 60, with a mean age of 35.

Statistical Information

P-Value

<0.05

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1155/2011/750249

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