Hib Serology in Childhood Leukaemia
Author Information
Author(s): Groves F D, Sinha D, Kayhty H, Goedert J J, Levine P H
Primary Institution: Medical University of South Carolina
Hypothesis
Do children with acute lymphoblastic leukaemia have different antibody levels to Haemophilus influenzae type b compared to non-leukaemic controls?
Conclusion
Children with acute lymphoblastic leukaemia have lower antibody levels to Hib compared to non-leukaemic controls, especially at younger ages.
Supporting Evidence
- Antibody to Haemophilus influenzae type b was measured in children with acute lymphoblastic leukaemia.
- The study included a case-control design with 42 cases and 42 controls.
Takeaway
Kids with a type of blood cancer have different levels of a specific antibody compared to kids who are healthy.
Methodology
Antibody levels were measured in 42 children with acute lymphoblastic leukaemia and 42 non-leukaemic controls.
Participant Demographics
42 children with acute lymphoblastic leukaemia and 42 non-leukaemic hospital controls.
Statistical Information
P-Value
0.05
Statistical Significance
p=0.05
Digital Object Identifier (DOI)
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