Highlights from the 15th International Mouse Genome Conference
Author Information
Author(s): Jo Wixon, Kerstin Lindblad Toh, Shaying Zhao, Muriel Davisson, Anne-Marie Mallon, Jim Thomas, Gene Myers, Tim Wiltshire, Lee Smith, Harukazu Suzuki, William Stanford, Jean Weissenbach, Tim Hubbard, Deanna Church, Carol Bult, Monica Justice, Karen Steel, Heinrich Flaswinkel, John Schimenti, Jay Vivian, Emma Coghill, Allan Balmain
Conclusion
The conference highlighted significant advancements in mouse genome sequencing and comparative genomics, with ongoing projects aiming for higher coverage and better annotation.
Supporting Evidence
- Genome sequencing projects aim for >99% coverage by early 2003.
- Comparative analysis shows significant conservation between human and mouse genomes.
- High-density oligonucleotide arrays have been used to study gene expression in various tissues.
Takeaway
Scientists are working hard to understand the mouse genome, which helps us learn more about human genetics too.
Methodology
Various presentations discussed genome sequencing, comparative analysis, and gene expression studies using high-density oligonucleotide arrays and BAC fingerprinting.
Limitations
The studies are ongoing, and some data is still being assembled and analyzed.
Digital Object Identifier (DOI)
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