Phylogenetic and Pathotypical Analysis of Two Virulent Newcastle Disease Viruses Isolated from Domestic Ducks in China
2011

Analysis of Newcastle Disease Viruses from Ducks in China

publication 10 minutes Evidence: moderate

Author Information

Author(s): Zhang Shouping, Wang Xiaoting, Zhao Changguang, Liu Dehua, Hu Yanxin, Zhao Jixun, Zhang Guozhong

Primary Institution: Key Laboratory of Animal Epidemiology and Zoonosis, College of Veterinary Medicine, Ministry of Agriculture, China Agricultural University, Beijing, People's Republic of China

Hypothesis

What are the characteristics and pathogenicity of Newcastle disease viruses isolated from domestic ducks in China?

Conclusion

The study found that two Newcastle disease viruses from ducks in China are highly pathogenic to chickens and suggest that ducks may also be susceptible to the virus.

Supporting Evidence

  • Both NDV isolates were found to be velogenic strains with severe pathogenicity in chickens.
  • One isolate demonstrated some pathogenicity in domestic ducks.
  • Phylogenetic analysis revealed that the isolates clustered with class II NDVs.

Takeaway

Scientists studied viruses from ducks that can make chickens very sick. They found that these viruses can also affect ducks, which is surprising.

Methodology

The study involved isolating and characterizing two Newcastle disease viruses from ducks, assessing their pathogenicity in chickens and ducks, and conducting phylogenetic analysis.

Limitations

The study primarily focused on two isolates and may not represent all circulating strains in ducks.

Participant Demographics

The study involved domestic ducks and chickens from China.

Digital Object Identifier (DOI)

10.1371/journal.pone.0025000

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