Vitamin C Reduces Resistin Levels in Healthy Individuals
Author Information
Author(s): Bo Simona, Ciccone Giovannino, Durazzo Marilena, Gambino Roberto, Massarenti Paola, Baldi Ileana, Lezo Antonela, Tiozzo Elisa, Pauletto Daniela, Cassader Maurizio, Pagano Gianfranco
Primary Institution: University of Turin
Hypothesis
Does short-term vitamin C supplementation affect resistin serum levels in healthy individuals?
Conclusion
Short-term vitamin C supplementation significantly reduces resistin levels in healthy individuals.
Supporting Evidence
- Vitamin C supplementation reduced resistin concentration from 4.3 to 2.9 ng/ml.
- The control group showed no significant change in resistin levels.
- Vitamin C levels increased significantly in the experimental group.
- Changes in resistin levels were inversely related to changes in vitamin C levels.
Takeaway
This study found that taking vitamin C can lower a substance called resistin in the blood, which might be important for health.
Methodology
A randomized prospective open trial with 80 healthy participants receiving either vitamin C or no treatment for two weeks.
Potential Biases
Participants were not blinded to their group assignment, which could introduce bias.
Limitations
The lack of a placebo control group may have influenced participants' behavior and responses.
Participant Demographics
Healthy European-descent volunteers aged 20–50 years.
Statistical Information
P-Value
p < 0.001
Confidence Interval
95% CI −1.87, −1.03
Statistical Significance
p < 0.001
Digital Object Identifier (DOI)
Want to read the original?
Access the complete publication on the publisher's website