Impact of computerized physician order entry on medication prescription errors in the intensive care unit: a controlled cross-sectional trial
2006

Impact of Computerized Physician Order Entry on Medication Errors in ICU

Sample size: 90 publication Evidence: high

Author Information

Author(s): Colpaert Kirsten, Claus Barbara, Somers Annemie, Vandewoude Koenraad, Robays Hugo, Decruyenaere Johan

Primary Institution: Ghent University Hospital, Belgium

Hypothesis

Does the introduction of a computerized ICU system reduce medication prescription errors?

Conclusion

The ICU computerization significantly decreased the occurrence and severity of medication errors.

Supporting Evidence

  • The incidence of medication prescription errors was significantly lower in the computerized unit compared to the paper-based unit.
  • Minor medication prescription errors decreased from 18.3% in the paper-based unit to 0.7% in the computerized unit.
  • Patients with renal failure experienced a three-fold reduction in serious medication prescription errors in the computerized unit.

Takeaway

Using a computer system to write down medicine orders helps doctors make fewer mistakes when giving medicine to patients in the ICU.

Methodology

A controlled cross-sectional trial comparing a computerized unit to paper-based units in a 22-bed ICU, with medication orders validated by a clinical pharmacist.

Potential Biases

Potential bias from the clinical pharmacist's interventions to prevent errors.

Limitations

The study was conducted in only one tertiary care teaching hospital, limiting generalizability.

Participant Demographics

Patients in a 22-bed surgical ICU, with a mix of ages and conditions.

Statistical Information

P-Value

<0.001

Statistical Significance

p<0.001

Digital Object Identifier (DOI)

10.1186/cc3983

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