Assessing Heart Function with MRI
Author Information
Author(s): Cao JJ, Wang Yi, McLaughlin Jeannette, Haag Elizabeth, Passick Michael, Toole Rena, Cheng Joshua Y, Lachman Justine, Reichek Nathaniel
Primary Institution: St Francis Hospital, Roslyn, NY, USA
Hypothesis
The study investigates the hemodynamic correlates of contrast transit time within the left atrium in patients with left ventricular systolic dysfunction.
Conclusion
nLATT by dynamic MRI may be a valuable non-invasive marker of LV filling pressure in patients with LV systolic dysfunction.
Supporting Evidence
- nLATT correlated strongly with LV early diastolic pressure (r=0.893, p=0.001).
- nLATT was significantly prolonged in patients with LV systolic dysfunction compared to normal controls (p<0.001).
- Using a linear regression equation, LVEDP was estimated in the noninvasive cohort.
Takeaway
Doctors can use a special MRI technique to see how well the heart is filling with blood in patients who have heart problems.
Methodology
The study involved 10 subjects undergoing heart catheterization and 48 subjects undergoing noninvasive evaluation, with measurements taken before and after CMR.
Participant Demographics
Patients with left ventricular systolic dysfunction and normal controls.
Statistical Information
P-Value
p<0.001
Statistical Significance
p<0.001
Digital Object Identifier (DOI)
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