Cervix Cancer Study in Singapore
Author Information
Author(s): J. Cuzick, B. De Stavola, D. McCance, T.H. Ho, G. Tan, H. Cheng, S.Y. Chew, Y.M. Salmon
Primary Institution: Imperial Cancer Research Fund
Hypothesis
Are the same risk factors for cervix cancer present in Singapore as in Western countries?
Conclusion
The study found that parity and number of sexual partners are significant risk factors for cervical cancer in Singapore.
Supporting Evidence
- Parity and number of sexual partners were identified as significant risk factors.
- Education level was found to correlate with lower risk.
- HPV DNA was detected in 37% of cases tested.
Takeaway
Women who have more children or more sexual partners are at a higher risk of getting cervix cancer.
Methodology
A case-control study with 135 cases and 135 controls, collecting data on reproductive history, smoking, and socio-economic status.
Potential Biases
Potential bias due to self-reported data and small sample sizes for certain groups.
Limitations
The study may not account for unrecorded sexual behavior of male partners.
Participant Demographics
Participants included Chinese, Indian, and Malay women in Singapore.
Statistical Information
P-Value
p<0.001
Confidence Interval
95% CI=0.27-2.12
Statistical Significance
p<0.001
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