Efficacy of defocus incorporated multiple segments (DIMS) lenses and low-dose atropine on retarding myopic shift among premyopic preschoolers: Protocol for a prospective, multicenter, randomized controlled trial
2024

Premyopia intervention using DIMS and low-dose atropine

Sample size: 234 publication 10 minutes Evidence: moderate

Author Information

Author(s): Yang Hsin-Yu, Tsai Der-Chong, Yang Yu-Chieh, Wang Chiao-Yu, Lee Chia-Wei, Huang Pei-Wei

Primary Institution: National Yang Ming Chiao Tung University

Hypothesis

This study aims to evaluate the efficacy of optical (DIMS lenses) and pharmacological (0.01% atropine) interventions in preventing myopia among premyopic preschoolers.

Conclusion

This trial will provide insights into myopia prevention strategies and inform new eye care policies for early identification and intervention in premyopic preschoolers.

Supporting Evidence

  • Childhood myopia is a significant public health concern in East Asia.
  • Premyopia is defined as a refractive state of an eye of > -0.50 diopters and ≤ 0.75 D.
  • Previous studies have shown that low-dose atropine can delay myopia onset.

Takeaway

The study is trying to find out if special glasses and eye drops can help young kids who are at risk of getting nearsighted.

Methodology

This is a randomized controlled trial with three groups: DIMS spectacles, 0.01% atropine, and usual care, involving 234 premyopic preschoolers.

Potential Biases

Potential biases may arise from parental reporting and participant dropouts.

Limitations

The study may face challenges in participant recruitment and adherence to treatment protocols.

Participant Demographics

234 premyopic, asymptomatic children aged 5 to 6 years.

Digital Object Identifier (DOI)

10.1371/journal.pone.0312935

Want to read the original?

Access the complete publication on the publisher's website

View Original Publication