Prevalence of Multidrug-Resistant Tuberculosis in Category II Patients
Author Information
Author(s): Sharma Surendra K., Kumar Sanjeev, Saha P.K., George Ninoo, Arora S.K., Gupta Deepak, Singh Urvashi, Hanif M., Vashisht R.P.
Primary Institution: All India Institute of Medical Sciences, New Delhi, India
Hypothesis
What is the prevalence of multidrug-resistant tuberculosis (MDR-TB) among Category II pulmonary tuberculosis patients?
Conclusion
The study found a significant prevalence of MDR-TB at 20.4% among Category II pulmonary tuberculosis patients.
Supporting Evidence
- 40 out of 196 patients had MDR-TB, indicating a prevalence of 20.4%.
- The mean age of MDR-TB patients was 33.25 years.
- 9 patients (22.5%) were female.
- 36 patients showed resistance to rifampicin and isoniazid.
Takeaway
This study shows that many patients who have had tuberculosis before are now getting a tougher version of the disease that is harder to treat.
Methodology
A cross-sectional, descriptive study involving sputum-positive Category II pulmonary TB patients diagnosed between 2005 and 2008.
Potential Biases
Referral bias due to the hospital-based nature of the study.
Limitations
The study is hospital-based, which may introduce referral bias, and results may not be applicable to all Category II patients in India.
Participant Demographics
Mean age of participants was 33.25 years, with 22.5% being female.
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