Generation Scotland: the Scottish Family Health Study; a new resource for researching genes and heritability
2006

Generation Scotland: the Scottish Family Health Study

Sample size: 50000 publication Evidence: moderate

Author Information

Author(s): Blair H Smith, Harry Campbell, Douglas Blackwood, John Connell, Mike Connor, Ian J Deary, Anna F Dominiczak, Bridie Fitzpatrick, Ian Ford, Cathy Jackson, Gillian Haddow, Shona Kerr, Robert Lindsay, Mark McGilchrist, Robin Morton, Graeme Murray, Colin Palmer, Jill P Pell, Stuart H Ralston, David St Clair, Frank Sullivan, Graham Watt, Roland Wolf, Alan Wright, David Porteous, Andrews D Morris

Primary Institution: University of Aberdeen

Hypothesis

The study aims to identify genetic variants accounting for variation in levels of quantitative traits underlying major common complex diseases in Scotland.

Conclusion

The study will create a large family-based cohort to research genetic factors related to health and disease in Scotland.

Supporting Evidence

  • The study aims to recruit a large family-based cohort to study genetic factors affecting health.
  • Participants will provide blood samples for DNA analysis and complete health questionnaires.
  • The study will link genetic data with health records for comprehensive analysis.

Takeaway

This study is like a big family reunion where scientists are trying to find out how our genes affect our health.

Methodology

The study will recruit a family-based cohort of up to 50,000 individuals across Scotland, collecting DNA and health data.

Potential Biases

Bias may arise from the selection of family members for participation.

Limitations

The study may face challenges in participant recruitment and maintaining confidentiality.

Participant Demographics

Participants will be individuals aged 35-55 years with at least one first-degree relative aged 18 or over.

Digital Object Identifier (DOI)

10.1186/1471-2350-7-74

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