Organic Papers
2011
Study of Gliquidone's Molecular Structure
publication
Evidence: moderate
Author Information
Author(s): Thomas Gelbrich, Mairi F. Haddow, Ulrich J. Griesser
Primary Institution: Institute of Pharmacy, University of Innsbruck
Conclusion
The study reveals that gliquidone forms hydrogen-bonded chains that are significant for its molecular structure.
Supporting Evidence
- Gliquidone is an anti-diabetic drug in the sulfonylurea class.
- The conformation of the sulfonyl urea fragment aligns with previous theoretical studies.
- H-bonded chains formed by gliquidone display glide symmetry.
Takeaway
Gliquidone, a diabetes medication, has a special structure that helps it work better by forming chains with other molecules.
Methodology
The crystal structure was analyzed using X-ray diffraction techniques.
Digital Object Identifier (DOI)
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