Prevalence of Helicobacter pylori Infection in Peptic Ulcer Patients in Kashmir
Author Information
Author(s): GH. JEELANI ROMSHOO, G.M. MALIK, J.A. BASU, M. YOUSUF BHAT, A.R. KHAN
Primary Institution: Government Medical College, Srinagar, Kashmir, India
Hypothesis
This study aimed to find out the prevalence of Helicobacter pylori in peptic ulcer disease in Kashmir.
Conclusion
A significant association between H. pylori infection and peptic ulcer disease was found, but other factors may also contribute to this endemic condition.
Supporting Evidence
- H. pylori was present in 76.09% of duodenal ulcer patients.
- Patients with duodenitis and multiple ulcers were 100% H. pylori positive.
- Only 33.33% of healthy volunteers tested positive for H. pylori.
Takeaway
The study found that many people with stomach ulcers in Kashmir have a germ called H. pylori, but there might be other reasons for their ulcers too.
Methodology
The study included 50 peptic ulcer patients and 30 healthy volunteers, using endoscopy and various tests to detect H. pylori.
Limitations
The study only took biopsy samples from one site, which may affect the prevalence rates.
Participant Demographics
50 PUD patients (42 males, 8 females) and 30 healthy volunteers (25 males, 5 females), aged 18-70 years.
Statistical Information
P-Value
p<0.001
Statistical Significance
p<0.001
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