Thyroid Hormones and Growth in Health and Disease
2011
Thyroid Hormones and Growth in Health and Disease
publication
Evidence: moderate
Author Information
Author(s): Tarım Ömer
Primary Institution: Uludağ University Faculty of Medicine, Division of Pediatric Endocrinology, Bursa, Turkey
Hypothesis
How do thyroid hormones regulate growth in health and disease?
Conclusion
Thyroid functions are affected by many systemic diseases, and growth retardation in these conditions is often multifactorial.
Supporting Evidence
- Thyroid hormones regulate growth by several mechanisms.
- Hypothyroidism is a well-known cause of growth retardation.
- Hyperthyroidism has been reported to accelerate growth in normal children.
- Alterations in thyroid physiology must be considered when evaluating growth in children with systemic disease.
Takeaway
Thyroid hormones help kids grow, but if they're sick, it can mess with their thyroid and slow down their growth.
Methodology
This paper reviews the literature about the regulatory role of thyroid hormones in growth, in health and disease.
Limitations
The mechanisms regulating growth during disease processes are complicated and multifactorial.
Digital Object Identifier (DOI)
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