Calf Cramp in Children with Charcot-Marie-Tooth Disease
Author Information
Author(s): Fiona Hawke, Monique Ryan, Robert Ouvrier, Joshua Burns
Primary Institution: The University of Sydney
Hypothesis
What are the potential therapeutic targets for calf cramp in children with Charcot-Marie-Tooth disease?
Conclusion
Calf cramp in children with Charcot-Marie-Tooth disease is associated with older age and certain measures of strength, but no lower limb measures were linked to cramp when accounting for age.
Supporting Evidence
- 26 out of 81 children reported calf cramp.
- Calf cramp was associated with older age and stronger hand grip.
- Children with calf cramp were more likely to experience hand tremors.
Takeaway
Some kids with a specific disease get cramps in their legs, and we found that older kids and those with stronger hands might have more cramps.
Methodology
Children aged 2-16 years with CMT1A were assessed for various physical measures and data was analyzed using correlation coefficients and Fischer's exact test.
Limitations
The study does not establish causation and is limited to observational data.
Participant Demographics
Children aged 2-16 years with Charcot-Marie-Tooth disease Type 1A.
Statistical Information
P-Value
p=0.004
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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