Esophagitis in Children with Celiac Disease
2011

Esophagitis in Children with Celiac Disease

Sample size: 49 publication Evidence: moderate

Author Information

Author(s): Wael N. Sayej, Razan AlKhouri, Robert D. Baker, Raza Patel, Susan S. Baker

Primary Institution: Women and Children's Hospital of Buffalo, University at Buffalo

Hypothesis

What is the prevalence of esophagitis in children with celiac disease?

Conclusion

There was no difference in the prevalence of esophagitis between children diagnosed with celiac disease and those without it.

Supporting Evidence

  • 19 of 49 children with celiac disease had esophagitis.
  • The prevalence of esophagitis in children with celiac disease was 39%.
  • 45% of patients who underwent upper endoscopy had esophagitis.

Takeaway

The study looked at kids with celiac disease to see if they also had esophagitis, and found that the rates were similar to kids without celiac disease.

Methodology

The study reviewed biopsy reports of children with celiac disease and compared them to those without, focusing on esophageal inflammation.

Limitations

The study is retrospective and limited to children who underwent endoscopy, which may not represent the general population.

Participant Demographics

The study included 49 children with celiac disease, aged 1-18 years, with a mean age of 9.7 years.

Statistical Information

P-Value

0.2526

Confidence Interval

95% CI (0.23–0.51)

Statistical Significance

p=0.2526

Digital Object Identifier (DOI)

10.5402/2011/489065

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