Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery
Author Information
Author(s): Buniello Annalisa, Suveges Daniel, Cruz-Castillo Carlos, Llinares Manuel Bernal, Cornu Helena, Lopez Irene, Tsukanov Kirill, Roldán-Romero Juan María, Mehta Chintan, Fumis Luca, McNeill Graham, Hayhurst James D, Martinez Osorio Ricardo Esteban, Barkhordari Ehsan, Ferrer Javier, Carmona Miguel, Uniyal Prashant, Falaguera Maria J, Rusina Polina, Smit Ines, Schwartzentruber Jeremy, Alegbe Tobi, Ho Vivien W, Considine Daniel, Ge Xiangyu, Szyszkowski Szymon, Tsepilov Yakov, Ghoussaini Maya, Dunham Ian, Hulcoop David G, McDonagh Ellen M, Ochoa David
Primary Institution: Open Targets, Wellcome Genome Campus, Hinxton, Cambridgeshire CB10 1SD, UK
Conclusion
The Open Targets Platform has been significantly enhanced to improve user experience and facilitate the identification and prioritization of drug targets.
Supporting Evidence
- The Platform has expanded its data sources to improve drug target identification.
- New features allow users to prioritize targets based on various factors.
- Enhanced understanding of genetic variations aids in identifying drug targets.
- Integration of literature mining helps extract valuable information for drug discovery.
- User engagement has been promoted through outreach and training materials.
Takeaway
The Open Targets Platform helps scientists find and prioritize drug targets to develop new medicines by providing a lot of useful data and tools.
Methodology
The Platform integrates data from various public sources to assist in drug target identification and prioritization.
Digital Object Identifier (DOI)
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