Monitoring Adverse Drug Reactions in Cardiology Patients
Author Information
Author(s): Kaur Sharminder, Kapoor Vinod, Mahajan Rajiv, Lal Mohan, Gupta Seema
Primary Institution: Government Medical College, Jammu
Hypothesis
What is the incidence, severity, and causality of adverse drug reactions in hospitalized patients with cardiovascular disease?
Conclusion
One in five cardiac patients experiences adverse drug reactions, indicating a serious issue, but many of these reactions can be avoided.
Supporting Evidence
- 208 adverse drug reactions were reported from 188 patients.
- 33% of patients were hospitalized primarily due to ADRs.
- Type A reactions were the most common, indicating they are often avoidable.
- Statistically significant differences in ADR incidence were found based on age and gender.
Takeaway
Many heart patients have bad reactions to their medications, but most of these reactions can be prevented.
Methodology
A prospective, observational study was conducted over one year, registering 966 indoor cardiology patients and monitoring adverse drug reactions through spontaneous reporting and intensive monitoring.
Potential Biases
Potential bias due to reliance on physician reporting and patient recall for ADRs.
Limitations
The study only included indoor patients and could not assess outcomes after drug withdrawal.
Participant Demographics
The study included 966 patients, with a mean age of 61 years, 69.5% male and 30.5% female.
Statistical Information
P-Value
<0.05
Confidence Interval
1.47–2.91
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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