Progress in the pathogenic mechanism, histological characteristics of hereditary dentine disorders and clinical management strategies
2024

Understanding Hereditary Dentine Disorders

publication Evidence: moderate

Author Information

Author(s): Xue Qing, Wu Zhina, Zhao Yinuo, Wei Xiaoxi, Hu Min

Primary Institution: Hospital of Stomatology, Jilin University, Changchun, China

Hypothesis

The review aims to clarify the pathogenic mechanisms and clinical management strategies for hereditary dentine disorders.

Conclusion

This review highlights the need for improved recognition and understanding of hereditary dentine disorders to enhance clinical management and patient quality of life.

Supporting Evidence

  • Hereditary dentine disorders are autosomal dominant diseases affecting dentine development.
  • Dentinogenesis imperfecta (DGI) and dentine dysplasia (DD) are the main types of these disorders.
  • Genetic counseling and testing are recommended for affected individuals.

Takeaway

Hereditary dentine disorders are genetic issues that affect teeth, making them weak and discolored, and this review helps doctors understand and treat these problems better.

Methodology

This is a review article summarizing existing literature on hereditary dentine disorders.

Limitations

The review acknowledges the limited understanding of the disease and the need for further research.

Digital Object Identifier (DOI)

10.3389/fcell.2024.1474966

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