In Utero Transmission of Group B Streptococcus
Author Information
Author(s): Kathleen Robischon, Marvin S. Amstey
Primary Institution: University of Rochester School of Medicine and Dentistry
Hypothesis
Can Group B Streptococcus be transmitted hematogenously in a twin gestation?
Conclusion
The study suggests that Group B Streptococcus can be transmitted through the placenta rather than just through the maternal genital tract.
Supporting Evidence
- One twin had GBS sepsis while the other did not, despite prolonged rupture of membranes.
- The pathology confirmed chorioamnionitis in the infected twin's placenta.
- The unruptured twin was infected, suggesting an alternative transmission route.
Takeaway
In this case, one twin got sick from a germ while the other twin stayed healthy, even though one had a broken water bag. This shows that germs can spread in different ways than we thought.
Methodology
Case report of a twin gestation with one twin showing signs of GBS infection and the other not.
Limitations
This is a single case report, which may not be generalizable.
Participant Demographics
30-year-old gravida with a twin gestation.
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